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Research Manager Downstream Processing

PURATOS in ANDENNE
time Online sinds 2 november 2024 - Vaste jobs

Your Mission



In the heart of Puratos' R&D site in Andenne, you oversee Downstream Processing (DSP) projects, dedicated to the recovery of valuable proteins and enzymes post-fermentation.Your role extends to scaling up laboratory processes to industrial plant standards, emphasizing meticulous analysis and downstream procedures.Collaborating closely with the bioprocess manager, you lead the charge in driving process and technological improvements, ensuring efficiency and innovation.Additionally, you provide crucial support for the seamless transfer of technology into manufacturing or quality control, spearheading impactful technology transfer programs.



What you will do



- You will be exploring and innovating new DSP to enhance Puratos' processes for enzyme and protein recovery after fermentation, encompassing techniques such as MF, UF, chromatography, and sterile filtration.


- You will be responsible for the design and spearheading process development, characterization, scale-up (from benchtop to pilot unit), and tech transfer to onsite manufacturing facilities, all based in Andenne.


- You will have the chance to share your expertise and coach and mentor junior team members, offering guidance in downstream processing.


- You will apply bioengineering principles for troubleshooting, process modeling, and experimental design and execution.


- Under your supervision corrective actions and control plans to minimize variability and boost productivity in Downstream performance will be implemented.


- You will be collaborating and sharing expertise with cross-functional departments including QC, production, and regulatory teams.


- It is important to present updated results internally and potentially externally during meetings.


- You will be identifying, proposing, and executing analytical protocols for evaluating yields and recovery when necessary.